The AC-1204 Ketosis Strategy
Leveraging the physiological ketone system to provide fuel for the brain is a promising approach to addressing deficient glucose metabolism that is characteristic of Alzheimer’s disease.
A Look at the Data
An improvement in cognition has been consistently shown across multiple clinical studies
Phase 2a Study
•Improvement in cognition observed in patients who do not carry the APOE4 gene, 90 minutes after single dose administration.
• Improvement in cognition correlates with increased levels of ketones.
• Rapid improvement is based on energetics as neuronal metabolism immediately utilizes the available ketones.
Phase 2b Study
A multi-center, double blind, placebo-controlled 90-day study in subjects with mild to moderate Alzheimer’s disease